PRDM6 polyclonal antibody
Product Specifications
Background
PRDM6 is a zinc-finger domain containing protein that belongs to a family of PRDM (PRDI-BF1 and RIZ homology domain) proteins that act as agents for chromatin remodeling. The PRDM family is often associated with gene regulation and chromatin remodeling by way of their histone methyltransferase abilities. PRDM6 can function as a transcriptional repressor through interactions with the deacetylases and methyltransferases associated with Histone H4. PRDM6 is expressed in vascular precursor cells and likely has a role in development and differentiation of vascular tissue through its ability to remodel chromatin.
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
PFM3
Swiss Prot
Q9NQX0
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human PRDM6.
Conjugation
Unconjugated
Applications
WB
Dilution
WB 1:500 - 1:2000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 80 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
PRDM6 polyclonal antibody detects endogenous levels of PRDM6 protein.
Applications Notes
Western blot analysis of extracts of various cells, using PRDM6 antibody.
Host or Source
Rabbit
CAS Number
9007-83-4
Available Sizes
Curated Selection
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