AP3B1 polyclonal antibody
Product Specifications
Background
This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 2. Two transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
PE; HPS; HPS2; ADTB3; ADTB3A
Swiss Prot
O00203
Reactivity
Human, Mouse
Immunogen
Recombinant protein of human AP3B1.
Conjugation
Unconjugated
Applications
WB
Dilution
WB 1:500 - 1:2000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 132 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
AP3B1 polyclonal antibody detects endogenous levels of AP3B1 protein.
Applications Notes
Western blot analysis of extracts of various cells, using AP3B1 antibody.
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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