RBBP5 polyclonal antibody
Product Specifications
Background
This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Retinoblastoma-binding protein 5; RBBP-5; Retinoblastoma-binding protein RBQ-3; RBBP5; RBQ3
Swiss Prot
Q15291
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length Human RBBP5.
Conjugation
Unconjugated
Applications
WB IHC IF
Dilution
WB: 1:500~1:2000 IHC: 1:50~1:200 IF: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 70 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
RBBP5 polyclonal antibody detects endogenous levels of RBBP5 protein.
Applications Notes
Western blot analysis of extracts of various cell lines, using RBBP5 antibody.
Host or Source
Rabbit
CAS Number
9007-83-4
Available Sizes
Curated Selection
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