Trypsin-1 polyclonal antibody
Product Specifications
Background
Trypsin is a 24 kDa enzyme of the serine proteinase family. It is produced in the pancreas as an inactive precursor, trypsinogen, but the active enzyme is located in the gastrointestinal tract where it degrades proteins to large peptides. Trypsin prefers lysine and arginine residues. One of the substrates for trypsin is chymotrypsinogen which is cleaved to produce active chymotrypsin. High levels of immunoreactive trypsin in the bloodstream can indicate pancreatic malfunction and this indicator is used to screen for and diagnose Cystic Fibrosis.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Alpha-trypsin chain 2; Beta-trypsin; Cationic trypsinogen; Prss1; Serine protease 1; TRP1; TRY1; TRY1; TRYP1; Trypsin I
Swiss Prot
P07477
Reactivity
Human, Mouse
Immunogen
Recombinant full length Human Trypsin-1.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB: 1:500~1:2000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 35 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Trypsin-1 polyclonal antibody detects endogenous levels of Trypsin-1 protein.
Applications Notes
WesternBlot (WB) analysis of Trypsin-1 polyclonal antibody.
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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