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MARCH9 polyclonal antibody

Product Specifications

Background

MARCH9 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19) . MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH9 induces internalization of several membrane glycoproteins and directs them to the endosomal compartment (Bartee et al., 2004

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

RNF179; MARCH-IX

Swiss Prot

Q86YJ5

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human MARCH9

Conjugation

Unconjugated

Applications

WB

Dilution

WB 1:1000 - 1:2000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 43 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

MARCH9 polyclonal antibody detects endogenous levels of 42803 protein.

Applications Notes

Western blot analysis of extracts of various cells, using MARCH9 antibody.

Host or Source

Rabbit

Available Sizes

Curated Selection

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