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KCNV2 polyclonal antibody

Product Specifications

Background

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This member is identified as a 'silent subunit', and it does not form homomultimers, but forms heteromultimers with several other subfamily members. Through obligatory heteromerization, it exerts a function-altering effect on other potassium channel subunits. This protein is strongly expressed in pancreas and has a weaker expression in several other tissues.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Kv8.2; RCD3B; KV11.1

Swiss Prot

Q8TDN2

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human KCNV2

Conjugation

Unconjugated

Applications

WB

Dilution

WB 1:1000 - 1:2000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 75 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

KCNV2 polyclonal antibody detects endogenous levels of KCNV2 protein.

Applications Notes

Western blot analysis of extract of various cells, using KCNV2 antibody.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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