OLFM1 polyclonal antibody
Product Specifications
Background
The Olfactomedin family comprises a diverse group of secreted glycoproteins, which includes OLFM1 (Noelin-1), OLFM2 (Noelin-2), OLFM3 (Noelin-3), OLFM4 (Noelin-4), tiarin, pancortin, gliomedin and mycocilin. These proteins are implicated in the development of the nervous system. Specifically, OLFM1 and OLFM2 expression is observed in the neural plate and neural crest, as well as in the cranial ganglia in mouse at E8-10, and later in brain tissue and in the zone of polarizing activity in the limb. Overexpression of OLFM1 causes an excess of neural crest emigrations and prolonged neural crest production. OLFM2 participates in the regulation of the development of the anterior nervous system. An Arg144Gln mutation in OLFM2 has been implicated as a possible cause for open-angle glaucoma (OAG) .
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
AMY; NEUROBLASTOMA PROTEIN; Neuronal olfactomedin-related ER localized protein; Noe1; NOE1; Noel; Noel1; Noelin; Noelin1; OlfA; Olfactomedin 1; Olfactomedin-1; Olfm1; Pancortin 1; Pancortin
Swiss Prot
Q99784
Reactivity
Human, Mouse
Immunogen
Recombinant full length Human OLFM1.
Conjugation
Unconjugated
Applications
WB
Dilution
WB 1:500 - 1:2000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 72 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
OLFM1 polyclonal antibody detects endogenous levels of OLFM1 protein.
Applications Notes
Western blot analysis of extracts of various cell lines, using NUDT6 antibody.
Host or Source
Rabbit
Available Sizes
Curated Selection
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