What is the catalog number for ERI1 (D298) polyclonal antibody?

The catalog number for ERI1 (D298) polyclonal antibody is BS9202.

What sizes are available for ERI1 (D298) polyclonal antibody?

ERI1 (D298) polyclonal antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does ERI1 (D298) polyclonal antibody come in?

ERI1 (D298) polyclonal antibody is available in 2 different pack sizes.

Is ERI1 (D298) polyclonal antibody in stock?

ERI1 (D298) polyclonal antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

ERI1 (D298) polyclonal antibody

Product Specifications

Background

Helicase with RNase motif, more commonly designated Dicer, cleaves doublestranded RNA (dsRNA) in the RNA interference and small temporal RNA (stRNA) pathways, producing active small RNA components (siRNAs) which target the destruction of RNA and repress gene expression. Human Dicer cleaves dsRNA independent of ATP. The 3’-5’ exonuclease ERI-1, also known as Protein 3’hExo, degrades Histone mRNA after replication and may be involved in the regulation of RNA interference. ERI-1 has a high affinity for the stem-loop structure of replication-dependent Histone pre-mRNAs. It requires the 5’-ACCCA-3’ sequence present in stem-loop structure. ERI-1 and a stemloop binding protein (SLBP) target opposite faces of a unique highly conserved stem-loop RNA scaffold towards the 3’ end of Histone mRNA.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

3'EXO; THEX1; HEXO; Eri-1 homolog; 3'-5' exoribonuclease 1

Swiss Prot

Q8IV48

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 266-318 of Human ERI1.

Conjugation

Unconjugated

Applications

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 42 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

ERI1 (D298) polyclonal antibody detects endogenous levels of ERI1 protein.

Applications Notes

Western blot (WB) analysis of ERI1 pAb at 1:500 dilution Lane1:SGC7901 whole cell lysate (40ug) Lane2:A549 whole cell lysate (40ug) Lane3:U-87MG whole cell lysate (40ug)