ATF6B (S425) polyclonal antibody
Product Specifications
Background
ATF-6 is a member of the basic-leucine zipper family of transcription factors. Endoplasmic reticulum stress causes cleavage of transmembrane ATF-6 and transclocation of active ATF-6 to the nucleus. Soluble ATF-6 can exist as either an ATF-6β homodimer or an ATF-6α/β heterodimer. Binding of the ATF-6β homodimer or ATF-6α/β heterodimer to the nuclear transcription factor Y C (NF-YC) induces ER chaperone transcription.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Cyclic AMP-dependent transcription factor ATF-6 beta; cAMP-dependent transcription factor ATF-6 beta; Activating transcription factor 6 beta; ATF6-beta; Protein G13; cAMP response element-binding protein-related protein; Creb-rp; cAMP-responsive element-binding protein-like 1; Processed cyclic AMP-dependent transcription factor ATF-6 beta; ATF6B; CREBL1; G13; ATF-6β; ATF6β
Swiss Prot
Q99941
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 390-442 of Human ATF6B.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 90 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
ATF6B (S425) polyclonal antibody detects endogenous levels of ATF6B protein.
Applications Notes
Western blot (WB) analysis of ATF6B pAb at 1:500 dilution Lane1:The Embryo tissue lysate of Mouse (40ug) Lane2:C6 whole cell lysate (40ug) Lane3:CT-26 whole cell lysate (40ug) Lane4:HEK293T whole cell lysate (40ug) Lane5:DLD whole cell lysate (40ug) Lane6:A2780 whole cell lysate (40ug)
Host or Source
Rabbit
Available Sizes
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