What is the catalog number for Myc (K422) polyclonal antibody?

The catalog number for Myc (K422) polyclonal antibody is BS2462.

What sizes are available for Myc (K422) polyclonal antibody?

Myc (K422) polyclonal antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Myc (K422) polyclonal antibody come in?

Myc (K422) polyclonal antibody is available in 2 different pack sizes.

Is Myc (K422) polyclonal antibody in stock?

Myc (K422) polyclonal antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Myc (K422) polyclonal antibody

Product Specifications

Background

C-Myc-, N-Myc- and L-Myc-encoded proteins function in cell proliferation, differentiation and neoplastic disease. Myc proteins are nuclear proteins with relatively short half lives. Amplification of the c-Myc gene has been found in several types of human tumors including lung, breast and colon carcinomas, while the N-Myc gene has been found amplified in neuroblastomas. The presence of three sequence motifs in the c-Myc COOH terminus, including the leucine zipper, the helix-loop-helix and a basic region provided initial evidence for a sequence-specific binding function.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Myc proto-oncogene protein; Class E basic helix-loop-helix protein 39; bHLHe39; Proto-oncogene c-Myc; Transcription factor p64; MYC; BHLHE39

Swiss Prot

P01106

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 401-450 of Human Myc.

Conjugation

Unconjugated

Related Pathways

Warburg Effect, Signaling Pathways Activating p38 MAP KinaseCell Cycle Control G1 S Checkpoint, Glutamine Metabolism

Applications

WB IHC IF

Dilution

WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 55 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Myc (K422) polyclonal antibody detects endogenous levels of proto-oncogene c-Myc protein.

Applications Notes

Western blot (WB) analysis of MYC pAb at 1:1000 dilution Lane1:3T3-L1 whole cell lysate (40ug) Lane2:PC12 whole cell lysate (40ug) Lane3:A549 whole cell lysate (40ug) Lane4:Hela whole cell lysate (40ug) Lane5:HEK293T whole cell lysate (40ug)