CTSK polyclonal antibody

Product Specifications

Background

The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O . The aspartyl protease class is composed of cathepsins D and E . Cathepsin G is in the serine protease class . Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsin K expression is highest in bone, cartilage and skeletal muscle. The strongest mRNA levels are revealed in osteoclasts .

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Cathepsin K; Cathepsin O; Cathepsin O2; Cathepsin X; CTSK; CTSO; CTSO2

Swiss Prot

P43235

Reactivity

Human

Immunogen

A synthetic peptide corresponding to residues in Human CTSK

Conjugation

Unconjugated

Applications

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 43 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

CTSK polyclonal antibody detects endogenous levels of CTSK protein.

Applications Notes

Western blot (WB) analysis of CTSK pAb at 1:500 dilution Lane1:MCF-7 whole cell lysate (40ug) Lane2:A375 whole cell lysate (40ug) Lane3:HCT116 whole cell lysate (40ug)