BACH1 (L160) polyclonal antibody
Product Specifications
Background
BACH1 and BACH2, heterodimerization partners of MafK, are members of a novel family of BTB/POZ-basic region leucine zipper (bzip) factors. BACH1 and BACH2 have significant similarity to each other in BTB domain and Cap‘n’ collar-type bZip domain but are otherwise divergent. BACH1 appears ubiquitous, whereas BACH2 is restricted to monocytes, neuronal cells and is abundantly expressed in the early stages of B-cell differentiation. BACH2, a 841 amino acid polypeptide, is an Nrf2-related transcription repressor and a tissue-specific partner of the Maf oncoprotein family.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Transcription regulator protein BACH1; BTB and CNC homolog 1; HA2303; BACH1
Swiss Prot
O14867
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 131-180 of Human BACH1.
Conjugation
Unconjugated
Applications
WB IHC IF
Dilution
WB: 1:500~1000 IHC: 1:50~1:200 IF: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 90 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
BACH1 (L160) polyclonal antibody detects endogenous levels of BACH1 protein.
Applications Notes
Western blot (WB) analysis of IKBKG pAb at 1:500 dilution Lane1:The lung tissue lysate of Mouse (40ug) Lane2:Aml-12 whole cell lysate (40ug) Lane3:PMVEC whole cell lysate (40ug) Lane4:HEK293T whole cell lysate (40ug) Lane5:Hela whole cell lysate (40ug) Lane6:SHSY5Y whole cell lysate (40ug)
Host or Source
Rabbit
Available Sizes
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