GDI2 polyclonal antibody
Product Specifications
Background
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.
Product Name Alternative
Rab GDP dissociation inhibitor beta; Rab GDI beta; Guanosine diphosphate dissociation inhibitor 2; GDI-2; GDI2; RABGDIB
Swiss Prot
P50395
Reactivity
Human, Rat, Mouse
Immunogen
Synthetic peptide, corresponding to Human GDI2.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB: 1:500~1:1000 IHC:1:50~1:100
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 50 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
GDI2 polyclonal antibody detects endogenous levels of GDI2 protein.
Applications Notes
Western blot (WB) analysis of GDI2 polyclonal antibody at 1:500 dilution LaneA:A549 whole cell lysate (40ug) LaneB:Hela whole cell lysate (40ug) LaneC:LOVO whole cell lysate (40ug) LaneD:BV2 whole cell lysate (40ug) LaneE:PC12 whole cell lysate (40ug)
Host or Source
Rabbit
Available Sizes
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