Kv5.1 polyclonal antibody
Product Specifications
Background
KCNF1 (potassium voltage-gated channel subfamily F member 1) is a multipass membrane-bound protein that acts as an ion channel and is generally expressed as a heterotetramer of potassium channeling proteins. Formerly known as kH1, KCNF1 is usually found as a heteromer with three other potassium channel proteins, KCNG3, KV6.3 and KCNV2. As a potassium channel protein, KCNF1 plays a role in regulating apoptosis and proliferation of pulmonary artery smooth muscle (PASM) cells. Bone morphogenetic proteins (BMPs) restrict proliferation and can induce apoptosis in normal human PASM cells and will upregulate expression of KCNF1 in PASM cells in vitro. KCNF1 is expressed in heart, brain, liver, skeletal muscle, kidney and pancreas.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.
Product Name Alternative
Potassium voltage-gated channel subfamily F member 1; Voltage-gated potassium channel subunit Kv5.1; Kh1; KCNF1
Swiss Prot
Q9H3M0
Reactivity
Human, Rat, Mouse
Immunogen
Synthetic peptide, corresponding to Human Kv5.1.
Conjugation
Unconjugated
Applications
WB
Dilution
WB:1:500~1:1000
Purity
The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 55 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -25°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Kv5.1 polyclonal antibody detects endogenous levels of Kv5.1 protein.
Applications Notes
Western blot (WB) analysis of Kv5.1 polyclonal antibody at 1:500 dilution LaneA:COS-7 whole cell lysate LaneB:Panc1 whole cell lysate LaneC:The heart tissue lysate of Mouse LaneD:The heart tissue lysate of Rat
Host or Source
Rabbit
Available Sizes
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