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INT2 polyclonal antibody

Product Specifications

Background

Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable) . Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Product Name Alternative

Integrator complex subunit 2; Int2; INTS2; KIAA1287

Swiss Prot

Q9H0H0

Reactivity

Human, Rat, Mouse

Immunogen

Synthetic peptide, corresponding to Human INT2.

Conjugation

Unconjugated

Applications

WB IHC

Dilution

WB:1:500~1:1000 IHC:1:50~1:200

Purity

The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 134 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

INT2 polyclonal antibody detects endogenous levels of INT2 protein.

Applications Notes

Western blot (WB) analysis of INT2 polyclonal antibody at 1:500 dilution LaneA:HepG2 whole cell lysate LaneB:HCT116 whole cell lysate LaneC:Hela whole cell lysate LaneD:PC12 whole cell lysate LaneE:CT-26 whole cell lysate

Host or Source

Rabbit

CAS Number

9007-83-4

Available Sizes

Curated Selection

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