INT2 polyclonal antibody
Product Specifications
Background
Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable) . Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.
Product Name Alternative
Integrator complex subunit 2; Int2; INTS2; KIAA1287
Swiss Prot
Q9H0H0
Reactivity
Human, Rat, Mouse
Immunogen
Synthetic peptide, corresponding to Human INT2.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB:1:500~1:1000 IHC:1:50~1:200
Purity
The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 134 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
INT2 polyclonal antibody detects endogenous levels of INT2 protein.
Applications Notes
Western blot (WB) analysis of INT2 polyclonal antibody at 1:500 dilution LaneA:HepG2 whole cell lysate LaneB:HCT116 whole cell lysate LaneC:Hela whole cell lysate LaneD:PC12 whole cell lysate LaneE:CT-26 whole cell lysate
Host or Source
Rabbit
Available Sizes
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