HnRNP UL2 polyclonal antibody
Product Specifications
Background
Heterogeneous nuclear ribonucleoprotein U-like protein 2, is a multifunctional protein and previous studies have implicated it in the modulation of p53 transcriptional activity, although this has been rather poorly understood. Results presented here demonstrate that hnRNPUL-1 represses p53 transcriptional activity and negatively regulates p21 levels. This is consistent with the depletion of hnRNPUL-1 leading to an increase in cells arrested in G1/S. Together these results confirm that hnRNPUL-1 acts as a p53 co-repressor with specific cellular targets.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.
Product Name Alternative
Heterogeneous nuclear ribonucleoprotein U-like protein 2; Scaffold-attachment factor A2; SAF-A2; HNRNPUL2; HNRPUL2
Swiss Prot
Q1KMD3
Reactivity
Human, Rat, Mouse
Immunogen
Synthetic peptide, corresponding to Human hnRNP UL2.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB:1:500~1:1000 IHC:1:50~1:200
Purity
The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 90 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
HnRNP UL2 polyclonal antibody detects endogenous levels of hnRNP UL2 protein.
Applications Notes
Western blot (WB) analysis of hnRNP UL2 polyclonal antibody at 1:500 dilution LaneA:Jurkat whole cell lysate LaneB:HepG2 whole cell lysate LaneC:MEF whole cell lysate LaneD:PC12 whole cell lysate
Host or Source
Rabbit
Available Sizes
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