GPR56 polyclonal antibody
Product Specifications
Background
Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Plays a role in the maintenance of hematopoietic stem cells and/or leukemia stem cells in bone marrow niche. Plays a critical role in cancer progression by inhibiting VEGFA production threreby inhibiting angiogenesis through a signaling pathway mediated by PRKCA. Plays an essential role in testis development.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Adhesion G-protein coupled receptor G1; G-protein coupled receptor 56; Protein TM7XN1; ADGRG1 N-terminal fragment; ADGRG1 NT; GPR56 N-terminal fragment; GPR56 NT; GPR56 (N) ; GPR56 extracellular subunit; GPR56 subunit alpha; ADGRG1 C-terminal fragment; ADGRG1 CT; GPR56 C-terminal fragment; GPR56 CT; GPR56 (C) ; GPR56 seven-transmembrane subunit; GPR56 7TM; GPR56 subunit beta; ADGRG1; GPR56; TM7LN4; TM7XN1; UNQ540; PRO1083
Swiss Prot
Q9Y653
Reactivity
Human, Rat
Immunogen
Synthetic peptide, corresponding to Human GPR56.
Conjugation
Unconjugated
Applications
WB IF
Dilution
WB:1:500~1:1000 IF:1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 65 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
GPR56 polyclonal antibody detects endogenous levels of GPR56 protein.
Applications Notes
Western blot (WB) analysis of GPR56 polyclonal antibody at 1:500 dilution LaneA:C6 whole cell lysate LaneB:Hela whole cell lysate
Host or Source
Rabbit
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
ARP31171_P050-FITC 100 µL
E2F1 Antibody - middle region : FITC (ARP31171_P050-FITC)
Ask
View Details MBS6323850-01 0.2 mL
NARG2, NT (NARG2, BRCC1, NMDA receptor-regulated protein 2) (FITC)
Ask
View Details 
MBS6323850-02 5x 0.2 mL
NARG2, NT (NARG2, BRCC1, NMDA receptor-regulated protein 2) (FITC)
Ask
View Details 