GPR27 polyclonal antibody
Product Specifications
Background
G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation) . GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. GPRs all have seven membrane-spanning domains and extracellular loops that can be glycosylated. These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure. SREB1 (super conserved receptor expressed in brain 1), also known as GPR27 (G protein-coupled receptor 27), belongs to the SREB subfamily of GPRs that are expressed in the central nervous system. SREB1 may function as an amine-like GPR.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Probable G-protein coupled receptor 27; Super conserved receptor expressed in brain 1; GPR27; SREB1
Swiss Prot
Q9NS67
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to Human GPR27.
Conjugation
Unconjugated
Applications
WB IHC IF
Dilution
WB:1:500~1:1000 IHC:1:50~1:200 IF:1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 36 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
GPR27 polyclonal antibody detects endogenous levels of GPR27 protein.
Applications Notes
Western blot (WB) analysis of GPR27 polyclonal antibody at 1:500 dilution LaneA:HEK293T whole cell lysate LaneB:SGC7901 whole cell lysate LaneC:The Lung tissue lysate of Mouse
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
