GPR174 polyclonal antibody

Product Specifications

Background

G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR174 (G protein-coupled receptor 174), also known as FKSG79, is a 333 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor 1 family and is thought to function as a receptor for G protein-coupled purines.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

FKSG79; GPCR17; Probable G-protein coupled receptor 174

Swiss Prot

Q9BXC1

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to Human GPR174.

Conjugation

Unconjugated

Applications

WB IF

Dilution

WB:1:500~1:1000 IF:1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 39 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

GPR174 polyclonal antibody detects endogenous levels of GPR174 protein.

Applications Notes

Western blot (WB) analysis of GPR174 polyclonal antibody at 1:500 dilution LaneA:BV2 whole cell lysate LaneB:PC12 whole cell lysate LaneC:A549 whole cell lysate LaneD:Hela whole cell lysate