What is the catalog number for MMP1 polyclonal antibody?

The catalog number for MMP1 polyclonal antibody is BS62563.

What sizes are available for MMP1 polyclonal antibody?

MMP1 polyclonal antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does MMP1 polyclonal antibody come in?

MMP1 polyclonal antibody is available in 2 different pack sizes.

Is MMP1 polyclonal antibody in stock?

MMP1 polyclonal antibody is currently made to order / not held in immediate stock. Contact us for lead time.

MMP1 polyclonal antibody

Product Specifications

Background

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB) . MMP catalysis requires both calcium and zinc. MMP-9 (also designated 92 kDa type IV collagenase or gelatinase B) has been shown to degrade bone collagens in concert with MMP-1 (also designated interstitial collagenase, fibroblast collagenase or collagenase-1), and cysteine proteases and may play a role in bone osteoclastic resorption. MMP-1 is downregulated by p53, and abnormality of p53 expression may contribute to joint degradation in rheumatoid arthritis by regulating MMP-1 expression.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Interstitial collagenase; Fibroblast collagenase; Matrix metalloproteinase-1; MMP-1; 22 kDa interstitial collagenase; 27 kDa interstitial collagenase; MMP1; CLG

Swiss Prot

P03956

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to Human MMP1.

Conjugation

Unconjugated

Applications

Dilution

WB:1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 54 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

MMP1 polyclonal antibody detects endogenous levels of MMP1 protein.

Applications Notes

Western blot (WB) analysis of MMP1 polyclonal antibody at 1:500 dilution LaneA:HEK293T whole cell lysate LaneB:Hela whole cell lysate LaneC:The Kidney tissue lysate of Mouse LaneD:The Kidney tissue lysate of Rat