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ZNT9 polyclonal antibody

Product Specifications

Background

Zinc, an essential element required for cell proliferation and differentiation, plays a role in a diverse array of cellular functions, including acting as a cofactor for numerous enzymes and transcription factors and as a neuroregulator. The zinc transporter (ZnT) or solute carrier 30 (SLC30) family regulates the supply of zinc within cells, and its members are characterized by containing six membrane-spanning domains, a large histidine-rich intracellular loop, and a C-terminal tail. ZnT proteins also belong to the cation diffusion facilitator (CDF) transporter family of metal ion transporters. ZnT-9, also known as HUEL (human embryonic lung protein), GAC63 (GRIP1-associated coactivator 1) or SLC30 member 9, displays ubiquitous expression in fetal and adult tissues as well as cancer cell lines. ZnT-9 localizes to the cytoplasm and is translocated to the nucleus during S phase. ZnT-9 has the lowest homology with the other zinc transporters and may function as a DNA-binding protein.

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Zinc transporter 9; ZnT-9; Human embryonic lung protein; HuEL; Solute carrier family 30 member 9; SLC30A9; C4orf1; HUEL

Swiss Prot

Q6PML9

Reactivity

Human, Mouse

Immunogen

Synthetic peptide, corresponding to Human ZNT9.

Conjugation

Unconjugated

Applications

WB

Dilution

WB:1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 55 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

ZNT9 polyclonal antibody detects endogenous levels of ZNT9 protein.

Applications Notes

Western blot (WB) analysis of ZNT9 polyclonal antibody at 1:500 dilution LaneA:CT26 whole cell lysate LaneB:C6 whole cell lysate LaneC:HEK293T whole cell lysate LaneD:HepG2 whole cell lysate

Host or Source

Rabbit

CAS Number

9007-83-4

Available Sizes

Curated Selection

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