SNAT2 polyclonal antibody

Product Specifications

Background

The sodium-coupled neutral amino acid transporters (SNAT) of the SLC38 gene family include system A subtypes SNAT1, SNAT2 and SNAT4 and system N subtypes SNAT3 and SNAT5. The SLC38 transporters are essential for the uptake of nutrients, energy production, metabolism, detoxification and the cycling of neurotransmitters. SNAT2, also designated ATA2, PRO1068 and SAT2, is encoded by the human gene SLC38A2. The functional role of SNAT2 in the nervous system is unclear. Protein expression is notably enriched in the spinal cord and brain stem nuclei of the auditory system. System A transport proteins are also present in placental tissue. These SNAT proteins may play a significant role in fetal development and inhibition of the transport system has been associated with fetal growth retardation.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Sodium-coupled neutral amino acid transporter 2; Amino acid transporter A2; Protein 40-9-1; Solute carrier family 38 member 2; System A amino acid transporter 2; System A transporter 1; System N amino acid transporter 2; SLC38A2; ATA2; KIAA1382; SAT2; SNAT2

Swiss Prot

Q96QD8

Reactivity

Human, Mouse

Immunogen

Synthetic peptide, corresponding to Human SNAT2.

Conjugation

Unconjugated

Applications

Dilution

WB:1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 50 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

SNAT2 polyclonal antibody detects endogenous levels of SNAT2 protein.

Applications Notes

Western blot (WB) analysis of SNAT2 polyclonal antibody at 1:500 dilution LaneA:AML-12 whole cell lysate LaneB:HepG2 whole cell lysate LaneC:U-87MG whole cell lysate