PPFIBP1 polyclonal antibody
Product Specifications
Background
The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
L2; SGT2; hSGT2; hSgt2p
Swiss Prot
Q86W92
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to Human PPFIBP1.
Conjugation
Unconjugated
Applications
WB
Dilution
WB:1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 114 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
PPFIBP1 polyclonal antibody detects endogenous levels of PPFIBP1 protein.
Applications Notes
Western blot (WB) analysis of PPFIBP1 polyclonal antibody at 1:500 dilution LaneA:PC12 whole cell lysate LaneB:CT26 whole cell lysate LaneC:HEK293T whole cell lysate LaneD:A549 whole cell lysate
Host or Source
Rabbit
Available Sizes
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