VTI1A polyclonal antibody

Product Specifications

Background

The protein encoded by this gene is a member of the family of soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptors (SNAREs) that function in intracellular trafficking. This family member is involved in vesicular transport between endosomes and the trans-Golgi network. It is a vesicle-associated SNARE (v-SNARE) that interacts with target membrane SNAREs (t-SNAREs) . Polymorphisms in this gene have been associated with binocular function, and also with susceptibility to colorectal and lung cancers. A recurrent rearrangement has been found between this gene and the transcription factor 7-like 2 (TCF7L2) gene in colorectal cancers. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

MMDS3; MVti1; VTI1RP2; Vti1-rp2

Swiss Prot

Q96AJ9

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to Human VTI1A.

Conjugation

Unconjugated

Applications

Dilution

WB:1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 28 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

VTI1A polyclonal antibody detects endogenous levels of VTI1A protein.

Applications Notes

Western blot (WB) analysis of VTI1A polyclonal antibody at 1:500 dilution LaneA:PC12 whole cell lysate LaneB:AML-12 whole cell lysate LaneC:HCT116 whole cell lysate