CCP2 polyclonal antibody

Product Specifications

Background

Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Cytosolic carboxypeptidase 2; ATP/GTP-binding protein-like 2; AGBL2; CCP2

Swiss Prot

Q5U5Z8

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to Human CCP2.

Conjugation

Unconjugated

Applications

WB IHC

Dilution

WB:1:500~1:1000 IHC:1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 115 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

CCP2 polyclonal antibody detects endogenous levels of CCP2 protein.

Applications Notes

Western blot (WB) analysis of CCP2 polyclonal antibody at 1:500 dilution LaneA:AML-12 whole cell lysate LaneB:PC12 whole cell lysate LaneC:Hela whole cell lysate