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ATG4C polyclonal antibody

Product Specifications

Background

Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II) . Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE) -conjugated form, and has the capacity for the binding to autophagosomes.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

APG4 autophagy 4 homolog C (S. cerevisiae) ; APG4 autophagy 4 homolog C; APG4 C; APG4C; ATG 4C; ATG4 autophagy related 4 homolog C (S. cerevisiae) ; Atg4c; ATG4C; AUT (S. cerevisiae) like 1; cysteine endopeptidase; AUT like 1; cysteine endopeptidase (S. cerevisiae) ; AUT like 1; cysteine endopeptidase; AUT like 3 cysteine endopeptidase; AUT-like 3 cysteine endopeptidase; AUTL1; AUTL3; Autophagin 3; Autophagin-3; Autophagy related cysteine endopeptidase 3; Autophagy related protein 4 homolog C

Swiss Prot

Q96DT6

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to Human ATG4C.

Conjugation

Unconjugated

Applications

WB IHC IF

Dilution

WB:1:500~1:1000 IHC:1:50~1:200 IF:1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 50 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

ATG4C polyclonal antibody detects endogenous levels of ATG4C protein.

Applications Notes

Western blot (WB) analysis of ATG4C polyclonal antibody at 1:500 dilution LaneA:AML-12 whole cell lysate LaneB:The Testis tissue lysate of Rat LaneC:MCF-7 whole cell lysate LaneD:L02 whole cell lysate

Host or Source

Rabbit

Available Sizes

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