CDYL2 polyclonal antibody
Product Specifications
Background
CDY is a gene family expressed exclusively in the testis that localizes to a region of the Y chromosome frequently deleted in infertile males. CDY proteins contain two functional domains, an N-terminal chromodomain, possibly functioning in heterochromatin interactions, and a C-terminal domain, which resembles enoyl-CoA-isomerase, a protein involved in fatty acid oxidation. Furthermore, CDY proteins act as histone acetyltransferases with strong preference for Histone H4, a process required for the histone to proamine transition in spermatogenesis, consistent with the association with male infertility. Chromodomain Y-like protein 2 (CDYL2) is a related nuclear protein that is ubiquitously expressed with moderate levels in most tissues. The gene encoding CDYL2 is located on chromosome 16.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Chromodomain Y-like protein 2; CDY-like 2; CDYL2
Swiss Prot
Q8N8U2
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to Human CDYL2.
Conjugation
Unconjugated
Applications
WB IHC ICC
Dilution
WB:1:500~1:1000 IHC:1:50~1:200 ICC:1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 57 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CDYL2 polyclonal antibody detects endogenous levels of CDYL2 protein.
Applications Notes
Western blot (WB) analysis of CDYL2 polyclonal antibody at 1:500 dilution LaneA:CT26 whole cell lysate LaneB:PC12 whole cell lysate LaneC:Hela whole cell lysate LaneD:PC3 whole cell lysate
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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