Cytochrome P450 2W1 polyclonal antibody

Product Specifications

Background

P450 enzymes constitute a family of monooxygenase enzymes that are involved in the metabolism of a wide array of endogenous and xenobiotic compounds. There are currently 57 known active cytochrome P450 (CYP) genes and 58 known pseudogenes present in the human genome. Several P450 enzymes have been classified by sequence similarities as members of the CYP1A and CYP2A subfamilies. CYP2W1 is a 490 amino acid protein that belongs to the CYP2 family of cytochrome P450 proteins. These proteins are usually involved in the metabolism of foreign compounds. CYP2W1 metabolizes arachidonic acid and catalyzes the oxidation of indole. CP2W1 represents a tumor-specific P450 isoform that is universally conserved in vertebrates and is a potential drug target in cancer therapeutics.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Cytochrome P450 2W1; CYPIIW1; CYP2W1

Swiss Prot

Q8TAV3

Reactivity

Human

Immunogen

Synthetic peptide, corresponding to Human Cytochrome P450 2W1.

Conjugation

Unconjugated

Applications

WB IHC IF

Dilution

WB:1:500~1:1000 IHC:1:50~1:200 IF:1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .