NAP1 polyclonal antibody
Product Specifications
Background
Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFNB promoter activation via TICAM1.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
5-azacytidine-induced protein 2; NF-kappa-B-activating kinase-associated protein 1; Nak-associated protein 1; TILP; AZI2; NAP1; TBKBP2
Swiss Prot
Q9H6S1
Reactivity
Human
Immunogen
Synthetic peptide, corresponding to Human NAP1.
Conjugation
Unconjugated
Applications
WB IHC IF
Dilution
WB:1:500~1:1000 IHC:1:50~1:200 IF:1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 28 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
NAP1 polyclonal antibody detects endogenous levels of NAP1 protein.
Applications Notes
Western blot analysis of extracts of HepG2 cell line, using NAP1 polyclonal antibody.
Host or Source
Rabbit
Available Sizes
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