ZNF785 polyclonal antibody

Product Specifications

Background

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 688 (ZNF688) is a 276 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZNF688 contains two C2H2-type zinc fingers and one KRAB domain through which it is thought to be involved in DNA-binding and transcriptional regulation. Zinc finger protein 785 (ZNF785) is a 405 amino acid member of the Krüppel C2H2-type zinc-finger protein family. ZNF785 contains seven C2H2-type zinc fingers and one KRAB domain. Two isoforms of ZNF785 exist as a result of alternative splicing events.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Zinc finger protein 785; ZNF785

Swiss Prot

A8K8V0

Reactivity

Human

Immunogen

Synthetic peptide, corresponding to Human ZNF785.

Conjugation

Unconjugated

Applications

WB IHC

Dilution

WB:1:500~1:1000 IHC:1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .