CACNA1G polyclonal antibody
Product Specifications
Background
Voltage-dependent Ca2+ channels mediate Ca2+ entry into excitable cells in response to membrane depolarization, and they are involved in a variety of Ca2+-dependent processes, including muscle contraction, hormone or neurotransmitter release and gene expression. Calcium channels are highly diverse, multimeric complexes composed of an alpha-1 subunit, an intracellular beta subunit, a disulfide linked alpha-2/delta subunit and a transmembrane gamma subunit. Ca2+ currents are characterized on the basis of their biophysical and pharmacologic properties and include L-, N-, T-, P-, Q-, and R- types. T-type Ca2+ currents are activated and inactivated more rapidly and at more negative membrane potentials than other Ca2+ current types. T-type Ca2+ channels enhance odor sensitivity by lowering the threshold of spike generation in olfactory receptor cells (ORCs) .
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Voltage-dependent T-type calcium channel subunit alpha-1G; Cav3.1c; NBR13; Voltage-gated calcium channel subunit alpha Cav3.1; CACNA1G; KIAA1123
Swiss Prot
O43497
Reactivity
Human
Immunogen
A synthetic peptide corresponding to residues in Human CACNA1G.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 265 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CACNA1G polyclonal antibody detects endogenous levels of CACNA1G protein.
Applications Notes
Western blot (WB) analysis of CACNA1G pAb at 1:500 dilution Lane1:Myla2059 whole cell lysate (40ug) Lane2:Hela whole cell lysate (40ug) Lane3:A549 whole cell lysate (40ug)
Host or Source
Rabbit
Available Sizes
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