FARSLB polyclonal antibody
Product Specifications
Background
FARSLB (Phenylalanine--tRNA ligase beta chain), also known as FARSB, FRSB, PheHB or PheRS, is a 589 amino acid cytoplasmic protein that is the regulatory beta subunit of phenylalanine-tRNA synthetase. A highly conserved member of the aminoacyl-tRNA synthetase class IIc subfamily, FARSLB functions to enzymatically attach L-phenylalanine residues to terminal adenosines on tRNA (Phe) . This is an ATP-dependent reaction that yields AMP, a diphosphate and an L-phenylalanine-tagged tRNA (Phe) . FARSLB is expressed in brain, heart, kidney, pancreas, placenta and skeletal muscle and its expression is increased in malignant cell lines, suggesting a possible role for FARSLB in carcinogenesis.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Phenylalanine--tRNA ligase beta subunit; Phenylalanyl-tRNA synthetase beta subunit; PheRS; FARSB; FARSLB; FRSB; HSPC173
Swiss Prot
Q9NSD9
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human FARSLB.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 80 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
FARSLB polyclonal antibody detects endogenous levels of FARSLB protein.
Applications Notes
Western blot (WB) analysis of FARSB pAb at 1:500 dilution Lane1:CT-26 whole cell lysate (40ug) Lane2:C6 whole cell lysate (40ug) Lane3:PC3 whole cell lysate (40ug) Lane4:EC9706 whole cell lysate (40ug) Lane5:The pancreas tissue lysate of Mouse (40ug) Lane6:U-87MG whole cell lysate (40ug)
Host or Source
Rabbit
Available Sizes
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