ARMCX3 polyclonal antibody

The armadillo (ARM) repeat family of proteins are related to the Drosophilamelanogaster armadillo protein, a protein essential for wingless signal transduction. ARM proteins are involved in a variety of processes such as cellmigration, cell proliferation, tissue maintenance and tumorigenesis. They areintracellular proteins and function in signal transduction and cell structure. ARMCX3 (armadillo repeat containing, X-linked 3), also known as ALEX3 (ARM protein lost in epithelial cancers on chromosome X 3), is a single passmembrane protein belonging to the armadillo repeat family of proteins.ARMCX3 contains three ARM repeats and shares 60% sequence similaritywith the related proteins, ARMCX1 and ARMCX2. ARMCX3 is believed toplay a role in embryonic development and tissue maintenance and may alsofunction as a tumor suppressor.

Armadillo repeat-containing X-linked protein 3; ARM protein lost in epithelial cancers on chromosome X 3; Protein ALEX3; ARMCX3; ALEX3; BM-017, UNQ2517/PRO6007

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Western blot (WB) analysis of ARMCX3 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate (40ug) Lane2:Pancl whole cell lysate (40ug) Lane3:U-87MG whole cell lysate (40ug)