CPE polyclonal antibody

Product Specifications

Background

Carboxypeptidase E (CPE) Homo sapiens This gene encodes a member of the M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature peptidase. This peripheral membrane protein cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. This protein may also function independently of its peptidase activity, as a neurotrophic factor that promotes neuronal survival, and as a sorting receptor that binds to regulated secretory pathway proteins, including prohormones. Mutations in this gene are implicated in type 2 diabetes. [provided by RefSeq, Nov 2015]

CAS Number

9007-83-4

Structure Composition

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Product Name Alternative

CPE; Carboxypeptidase E; CPE; Carboxypeptidase H; CPH; Enkephalin convertase; Prohormone-processing carboxypeptidase

Swiss Prot

P16870

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from the C-terminal region of human CPE. AA range:427-476

Conjugation

Unconjugated

Applications

WB, IHC-p, IF (paraffin section), ELISA

Dilution

Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Modification

Unmodification

Molecular Weight

~ 53 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

CPE Polyclonal Antibody detects endogenous levels of CPE protein.

Applications Notes

Western Blot analysis of mouse brain cells using CPE Polyclonal Antibody.. Secondary antibody (catalog#: RS0002) was diluted at 1:20000

Host or Source

Rabbit

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

RC217382L4V 200 µL

SPDYE2 (NM_001031618) Human Tagged ORF Clone Lentiviral Particle

Ask

View Details

400504-01 50 µL

GCHFR

Ask

View Details

400504-02 100 µL

GCHFR

Ask

View Details

261308-01 50 mg

2-Aminoindane-2-carboxylic acid

Ask

View Details

261308-02 100 mg

2-Aminoindane-2-carboxylic acid

Ask

View Details

261308-03 250 mg

2-Aminoindane-2-carboxylic acid

Ask

View Details