C1S polyclonal antibody

Product Specifications

Background

Complement C1s (C1S) Homo sapiens This gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency. [provided by RefSeq, Mar 2009]

CAS Number

9007-83-4

Structure Composition

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Product Name Alternative

C1S; Complement C1s subcomponent; C1 esterase; Complement component 1 subcomponent s

Swiss Prot

P09871

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human C1S. AA range:541-590

Conjugation

Unconjugated

Applications

WB, IHC-p, IF (paraffin section), ELISA

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Modification

Unmodification

Molecular Weight

~ 77 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

C1s Polyclonal Antibody detects endogenous levels of C1s protein.

Applications Notes

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using C1S Antibody. The picture on the right is blocked with the synthesized peptide.