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NR4A3 polyclonal antibody

Product Specifications

Background

Nuclear receptor subfamily 4 group A member 3 (NR4A3) Homo sapiens This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator. The protein can efficiently bind the NGFI-B Response Element (NBRE) . Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes. The translocation breakpoints are associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (on chromosome 9) and either Ewing Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II, TATA Box-Binding Protein-Associated Factor, 68-KD (on chromosome 17), or Transcription factor 12 (on chromosome 15) . Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

CAS Number

9007-83-4

Structure Composition

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Product Name Alternative

NR4A3; CHN; CSMF; MINOR; NOR1; TEC; Nuclear receptor subfamily 4 group A member 3; Mitogen-induced nuclear orphan receptor; Neuron-derived orphan receptor 1; Nuclear hormone receptor NOR-1

Swiss Prot

Q92570

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human NR4A3. AA range:387-436

Conjugation

Unconjugated

Applications

WB, ELISA

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Modification

Unmodification

Molecular Weight

~ 65 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For

Specificity

NOR-1 Polyclonal Antibody detects endogenous levels of NOR-1 protein.

Applications Notes

Western blot analysis of lysates from COLO cells, using NR4A3 Antibody. The lane on the right is blocked with the synthesized peptide.

Host or Source

Rabbit

Available Sizes

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