EIF2AK1 polyclonal antibody

Product Specifications

Background

Eukaryotic translation initiation factor 2 alpha kinase 1 (EIF2AK1) Homo sapiens The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

CAS Number

9007-83-4

Structure Composition

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Product Name Alternative

EIF2AK1; HRI; KIAA1369; Eukaryotic translation initiation factor 2-alpha kinase 1; Heme-controlled repressor; HCR; Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase; Heme-regulated inhibitor; Hemin-sensitive initiation factor 2

Swiss Prot

Q9BQI3

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human EIF2AK1. AA range:571-620

Conjugation

Unconjugated

Applications

WB, IHC-p, IF (paraffin section), ELISA

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Modification

Unmodification

Molecular Weight

~ 71 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For

Specificity

HRI Polyclonal Antibody detects endogenous levels of HRI protein.

Applications Notes

Western Blot analysis of various cells using HRI Polyclonal Antibody

Host or Source

Rabbit

Available Sizes

Curated Selection

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