ARHGEF9 polyclonal antibody

Product Specifications

Background

Cdc42 guanine nucleotide exchange factor 9 (ARHGEF9) Homo sapiens The protein encoded by this gene is a Rho-like GTPase that switches between the active (GTP-bound) state and inactive (GDP-bound) state to regulate CDC42 and other genes. Defects in this gene are a cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]

CAS Number

9007-83-4

Structure Composition

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Product Name Alternative

ARHGEF9; ARHDH9; KIAA0424; Rho guanine nucleotide exchange factor 9; Collybistin; PEM-2 homolog; Rac/Cdc42 guanine nucleotide exchange factor 9

Swiss Prot

O43307

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human ARHGEF9. AA range:399-448

Conjugation

Unconjugated

Applications

IHC-p, IF (paraffin section), ELISA

Dilution

Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Modification

Unmodification

Molecular Weight

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

ARHGEF9 Polyclonal Antibody detects endogenous levels of ARHGEF9 protein.

Applications Notes

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using ARHGEF9 Antibody. The picture on the right is blocked with the synthesized peptide.