What is the catalog number for JHD3B polyclonal antibody?

The catalog number for JHD3B polyclonal antibody is BS65184.

What sizes are available for JHD3B polyclonal antibody?

JHD3B polyclonal antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does JHD3B polyclonal antibody come in?

JHD3B polyclonal antibody is available in 2 different pack sizes.

Is JHD3B polyclonal antibody in stock?

JHD3B polyclonal antibody is currently made to order / not held in immediate stock. Contact us for lead time.

JHD3B polyclonal antibody

Product Specifications

Background

Cofactor:Binds 1 Fe (2+) ion per subunit., domain:The 2 Tudor domains recognize and bind methylated histones. Double Tudor domain has an interdigitated structure and the unusual fold is required for its ability to bind methylated histone tails., function:Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate., similarity:Belongs to the JHDM3 histone demethylase family., similarity:Contains 1 JmjC domain., similarity:Contains 1 JmjN domain., similarity:Contains 2 PHD-type zinc fingers., similarity:Contains 2 Tudor domains.

CAS Number

9007-83-4

Structure Composition

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Product Name Alternative

KDM4B; JHDM3B; JMJD2B; KIAA0876; Lysine-specific demethylase 4B; JmjC domain-containing histone demethylation protein 3B; Jumonji domain-containing protein 2B

Swiss Prot

O94953

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human KDM4B. AA range:351-400

Conjugation

Unconjugated

Related Pathways

Epigenetic Writers and Erasers of Histone H3

Applications

IHC-p, IF (paraffin section), ELISA

Dilution

Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Modification

Unmodification

Molecular Weight

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

JMJD2B Polyclonal Antibody detects endogenous levels of JMJD2B protein.

Applications Notes

Immunohistochemistry analysis of paraffin-embedded human brain, using JHD3B Antibody. The picture on the right is blocked with the synthesized peptide.