MAP3K6 polyclonal antibody

Product Specifications

Background

Mitogen-activated protein kinase kinase kinase 6 (MAP3K6) Homo sapiens This gene encodes a serine/threonine protein kinase that forms a component of protein kinase-mediated signal transduction cascades. The encoded kinase participates in the regulation of vascular endothelial growth factor (VEGF) expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

CAS Number

9007-83-4

Structure Composition

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Product Name Alternative

MAP3K6; ASK2; MAPKKK6; MEKK6; Mitogen-activated protein kinase kinase kinase 6; Apoptosis signal-regulating kinase 2

Swiss Prot

O95382

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human MAP3K6. AA range:281-330

Conjugation

Unconjugated

Related Pathways

Signaling Pathways Activating p38 MAP Kinase

Applications

IHC-p, IF (paraffin section), ELISA

Dilution

Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Modification

Unmodification

Molecular Weight

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

MEK Kinase-6 Polyclonal Antibody detects endogenous levels of MEK Kinase-6 protein.

Applications Notes

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using MAP3K6 Antibody. The picture on the right is blocked with the synthesized peptide.