SH2D1B polyclonal antibody

Product Specifications

Background

SH2 domain containing 1B (SH2D1B) Homo sapiens By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001 [PubMed 11689425]) .[supplied by OMIM, Mar 2008]

CAS Number

9007-83-4

Structure Composition

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Product Name Alternative

SH2D1B; EAT2; SH2 domain-containing protein 1B; EWS/FLI1-activated transcript 2; EAT-2

Swiss Prot

O14796

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human SH2D1B. AA range:71-120

Conjugation

Unconjugated

Applications

IHC-p, IF (paraffin section), ELISA

Dilution

Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Modification

Unmodification

Molecular Weight

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

EAT-2 Polyclonal Antibody detects endogenous levels of EAT-2 protein.

Applications Notes

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using SH2D1B Antibody. The picture on the right is blocked with the synthesized peptide.