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Cullin 3 polyclonal antibody

Product Specifications

Background

Cullin 3 (CUL3) Homo sapiens This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]

CAS Number

9007-83-4

Structure Composition

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Product Name Alternative

CUL3; KIAA0617; Cullin-3; CUL-3

Swiss Prot

Q13618

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human Cullin 3. AA range:1-50

Conjugation

Unconjugated

Applications

WB, IHC-p, IF (paraffin section), ELISA

Dilution

Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Modification

Unmodification

Molecular Weight

~ 90 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

CUL-3 Polyclonal Antibody detects endogenous levels of CUL-3 protein.

Applications Notes

Western Blot analysis of various cells using CUL-3 Polyclonal Antibody diluted at 1: 1000

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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