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IRAK1 (Phospho-Thr387) polyclonal antibody

Product Specifications

Background

Interleukin 1 receptor associated kinase 1 (IRAK1) Homo sapiens This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

CAS Number

9007-83-4

Structure Composition

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Product Name Alternative

IRAK1; IRAK; Interleukin-1 receptor-associated kinase 1; IRAK-1

Swiss Prot

P51617

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human IRAK1 around the phosphorylation site of Thr387. AA range:353-402

Conjugation

Unconjugated

Applications

IF/ICC, ELISA

Dilution

WB 1:500-2000 Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Modification

Phosphorylation

Molecular Weight

/

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Phospho-IRAK-1 (T387) Polyclonal Antibody detects endogenous levels of IRAK-1 protein only when phosphorylated at T387.

Applications Notes

Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using IRAK1 (Phospho-Thr387) Antibody

Host or Source

Rabbit

Available Sizes

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