PARP2 polyclonal antibody
Product Specifications
Background
Involved in the base excision repair (BER) pathway, by catalyzing the poly (ADP-ribosyl) ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. Mediates serine ADP-ribosylation of target proteins following interaction with HPF1; HPF1 conferring serine specificity.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
PARP-2, hPARP-2, ARTD2, ADPRT-2, pADPRT-2, PARP2, ADPRT2, ADPRTL2, ADP ribosyltransferase like 2, ADP-ribosyltransferase diphtheria toxin-like 2, ADPRT 2, ADPRT-2, ADPRT2, ADPRTL 2, ADPRTL 3, ADPRTL2, ADPRTL3, ARTD2, hPARP 2, hPARP-2, hPARP2, NAD (+) ADP ribosyltransferase 2, NAD (+) ADP-ribosyltransferase 2, pADPRT 2, pADPRT-2, pADPRT2, PARP 2, PARP-2, PARP2, PARP2, Poly (ADP ribose) polymerase family member 2, Poly (ADP ribosyl) transferase like 2, poly (ADP-ribose) polymerase 2, Poly [ADP ribose] synthetase 2, Poly [ADP-ribose] polymerase 2, Poly (ADP ribose) synthetase, Poly[ADP-ribose] synthase 2
Swiss Prot
Q9UGN5
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to Human PARP2.
Conjugation
Unconjugated
Applications
WB
Dilution
WB:1:1000~1:2000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 66 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
PARP2 polyclonal antibody detects endogenous levels of PARP2 protein.
Applications Notes
Western blot (WB) analysis of PARP2 pAb at 1:1000 dilution Lane1:SHSY5Y whole cell lysate (40ug) Lane2:U-87MG whole cell lysate (40ug) Lane3:The heart tissue lysate of Rat (40ug) Lane4:H9C2 whole cell lysate (40ug)
Host or Source
Rabbit
Available Sizes
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