PARP2 polyclonal antibody

Involved in the base excision repair (BER) pathway, by catalyzing the poly (ADP-ribosyl) ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. Mediates serine ADP-ribosylation of target proteins following interaction with HPF1; HPF1 conferring serine specificity.

PARP-2, hPARP-2, ARTD2, ADPRT-2, pADPRT-2, PARP2, ADPRT2, ADPRTL2, ADP ribosyltransferase like 2, ADP-ribosyltransferase diphtheria toxin-like 2, ADPRT 2, ADPRT-2, ADPRT2, ADPRTL 2, ADPRTL 3, ADPRTL2, ADPRTL3, ARTD2, hPARP 2, hPARP-2, hPARP2, NAD (+) ADP ribosyltransferase 2, NAD (+) ADP-ribosyltransferase 2, pADPRT 2, pADPRT-2, pADPRT2, PARP 2, PARP-2, PARP2, PARP2, Poly (ADP ribose) polymerase family member 2, Poly (ADP ribosyl) transferase like 2, poly (ADP-ribose) polymerase 2, Poly [ADP ribose] synthetase 2, Poly [ADP-ribose] polymerase 2, Poly (ADP ribose) synthetase, Poly[ADP-ribose] synthase 2

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Western blot (WB) analysis of PARP2 pAb at 1:1000 dilution Lane1:SHSY5Y whole cell lysate (40ug) Lane2:U-87MG whole cell lysate (40ug) Lane3:The heart tissue lysate of Rat (40ug) Lane4:H9C2 whole cell lysate (40ug)