Phospho-RACGAP1 (Ser387) Polyclonal Antibody
Product Specifications
Background
Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
RACGAP1 (phospho S387) ; p-RACGAP1 (S387) ; p-RACGAP1 (Ser387) ; GAP; Gap1; GTPase activating protein; HsCYK 4; HsCYK4; ID GAP; KIAA1478; MgcRacGAP; Rac GTPase activating protein 1; RACGAP 1.
Swiss Prot
Q9H0H5
Reactivity
Human, Mouse, Rat, Dog, Cow
Immunogen
KLH conjugated synthesised phosphopeptide derived from human RACGAP1 around the phosphorylation site of Ser387:RI (p-S) GC
Conjugation
Unconjugated
Applications
WB
Dilution
WB=1:500-2000
Purity
Affinity purified by Protein A
Modification
Phosphorylation
Molecular Weight
71kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Phospho-RACGAP1 (Ser387) Polyclonal Antibody detects endogenous levels of RACGAP1 alpha protein only when phosphorylated at Ser387.
Applications Notes
Primary: Anti-phospho-RACGAP1 (Ser387) at 1/1000 dilution
Host or Source
Rabbit
Available Sizes
Curated Selection
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