CCDC125 Polyclonal Antibody
Product Specifications
Background
CCDC125, also known as KENAE, is a 511 amino acid protein expressed as two isoforms produced by alternative splicing and encoded by a gene mapping to human chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
CC125_HUMAN; CCDC125; Coiled-coil domain-containing protein 125; KENAE; y Protein kenae.
Swiss Prot
Q86Z20
Reactivity
Human, Mouse, Rat, Pig, Cow, Sheep
Immunogen
KLH conjugated synthetic peptide derived from human CCDC125:151-250/511
Conjugation
Unconjugated
Applications
WB
Dilution
WB=1:500-2000
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
52 kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CCDC125 Polyclonal Antibody detects endogenous levels of CCDC125 protein.
Applications Notes
Primary: Anti-CCDC125 at 1/1000 dilution
Host or Source
Rabbit
CAS Number
9007-83-4
Available Sizes
Curated Selection
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