ERN2 Polyclonal Antibody
Product Specifications
Background
ERN2, endoplasmic reticulum to nucleus signaling 2, induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. It is pro-apoptotic and appears to play no role in the unfolded-protein response, unlike closely related proteins.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
IRE1b; Endoplasmic reticulum to nucleus signaling 2; ER to nucleus signalling 2; ERN 2; Ern1; hIRE2p; Inositol requiring 1 beta; Inositol requiring protein 2; Ire1; Ire1 beta; IRE1 S. cerevisiae homolog of; IRE2; Serine/threonine protein kinase/endoribonuclease IRE2; ERN2_HUMAN.
Swiss Prot
O75460
Reactivity
Human, Mouse, Rat, Dog, Pig, Cow, Sheep
Immunogen
KLH conjugated synthetic peptide derived from human ERN2:465-550/926
Conjugation
Unconjugated
Applications
FCM
Dilution
Flow-Cyt=2ug/Test
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
98kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
ERN2 Polyclonal Antibody detects endogenous levels of ERN2 protein.
Host or Source
Rabbit
Available Sizes
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