ERN2 Polyclonal Antibody
Product Specifications
Background
ERN2, endoplasmic reticulum to nucleus signaling 2, induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. It is pro-apoptotic and appears to play no role in the unfolded-protein response, unlike closely related proteins.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
IRE1b; Endoplasmic reticulum to nucleus signaling 2; ER to nucleus signalling 2; ERN 2; Ern1; hIRE2p; Inositol requiring 1 beta; Inositol requiring protein 2; Ire1; Ire1 beta; IRE1 S. cerevisiae homolog of; IRE2; Serine/threonine protein kinase/endoribonuclease IRE2; ERN2_HUMAN.
Swiss Prot
O75460
Reactivity
Human, Mouse, Rat, Dog, Pig, Cow, Sheep
Immunogen
KLH conjugated synthetic peptide derived from human ERN2:465-550/926
Conjugation
Unconjugated
Applications
FCM
Dilution
Flow-Cyt=2ug/Test
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
98kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
ERN2 Polyclonal Antibody detects endogenous levels of ERN2 protein.
Host or Source
Rabbit
Available Sizes
Curated Selection
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